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During this same time, broad spectrum triazole and echinocandin antifungal agents have been developed and increasingly used. EUCAST deals with breakpoints and technical aspects of phenotypic in vitro antimicrobial susceptibility testing and functions as the breakpoint committee of EMA and ECDC. EUCAST does not deal with antibiotic policies, surveillance or containment of resistance or infection control. The Steering Committee is the decision making body.

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Committee to harmonize antimicrobial breakpoints, organized by ESCMID, ECDC and European national breakpoint committees. Subcommittees on antifungal susceptibility testing, susceptibility testing of anaerobes and interpretative reading and expert rules in susceptibility testing. Despite the importance of antimicrobial susceptibility testing (AST) for clinical management of infection and antimicrobial resistance (AMR) surveillance, the methodologies and breakpoints of the two most commonly used systems worldwide, Clinical and Laboratory Standards Institute (CLSI) and European Committee for Antimicrobial Susceptibility Testing (EUCAST), are far from harmonized. Committee to harmonize antimicrobial breakpoints, organized by ESCMID, ECDC and European national breakpoint committees. Subcommittees on antifungal susceptibility testing, susceptibility testing of anaerobes and interpretative reading and expert rules in susceptibility testing.

EUCAST deals with breakpoints and technical aspects of phenotypic in vitro antimicrobial susceptibility testing and functions as the breakpoint committee of EMA and ECDC. EUCAST does not deal with antibiotic policies, surveillance or containment of resistance or infection control.

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Breakpoint tables. Clinical breakpoints - bacteria (v 10.0) - pdf for printing (1 Jan - 31 Dec, 2020). Erratum: In the 2020 breakpoint table, imipenem-relebactam breakpoints under Enterobacterales, should read "valid except for Morganellaceae ". The European Committee on Antimicrobial Susceptibility Testing - EUCAST.

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Clinical breakpoints - bacteria (v 10.0) - pdf for printing (1 Jan - 31 Dec, 2020).

The Steering Committee is the decision making body. Two organisations have developed reference methods for the testing of fungal isolates and associated The subcommittee on antifungal susceptibility testing of the European Committee on Antibiotic Susceptibility Testing (EUCAST) has developed standards for susceptibility testing of fermentative Two organisations have developed reference methods for the testing of fungal isolates and associated Breakpoints for antifungal agents: An update from EUCAST focussing on echinocandins against Candida spp. and triazoles against Aspergillus spp. Maiken Arendrup.
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EUCAST DEFINITIVE DOCUMENT 10.1111/j.1469-0691.2007.01935.x EUCAST Definitive Document EDef 7.1: method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST)* CLSI and EUCAST susceptibility breakpoints for voriconazole and Candida albicans differ by one dilution (≤0.125 and ≤0.06 mg/liter, respectively) whereas the epidemiological cutoff values for EUCAST (ECOFF) and CLSI (ECV) are the same (0.03 mg/liter). We therefore determined the pharmacokinet … Clin Microbiol Infect 2011; 17: E27–E29 Abstract The European Committee on Antimicrobial Susceptibility Testing‐Subcommittee on Antifungal Susceptibility Testing (EUCAST‐AFST) has determined breakp EUCAST – recent documents • Expert Rules v 2.0 – CMI 2012 • EUCAST and PK/PD – CMI 2012 • EUCAST AFST - breakpoints and RDs for antifungal agents published (Candidae and Aspergillus). • Guidance on Stenotrophomons maltophilia 2012 • Guidance on direct AST 2012 • Guidance on systemic breakpoints for oral cephalosporins 2013-01-15 and compared their antifungal susceptibility according to clinical breakpoints defined by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) in 2013, and the Clinical and Laboratory Standards Institute (CLSI) in 2008 (old CLSI breakpoints) and 2012 The EUCAST Subcommittee on Antifungal Susceptibil-ity Testing analyzed the 24-h MIC values for WT Candida spp. and developed both epidemiologic cutoff values (ECVs or ECOFFs) and CBPs for voriconazole and selected species of Candida (EUCAST, 2008, 2010): the CBPs for S/R are MIC ≤0.125/N0.125 μg/mL to be applied to C. albicans, EUCAST technical note on isavuconazole breakpoints for Aspergillus, itraconazole breakpoints for Candida and updates for the antifungal susceptibility testing method documents.

Since 2016, isavuconazole EUCAST clinical breakpoints (BPs) and epidemiological cut-off values (ECOFFs) have been available for Aspergillus fumigatus, Aspergillus nidulans and Aspergillus terreus and ECOFFs only for Aspergillus flavus and Aspergillus niger. 1 These BPs and ECOFFs have been adopted for classification of contemporary Aspergillus isolates as susceptible/intermediate/resistant (S/I/R) and wildtype/non-wildtype, respectively.
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Subcommittees on antifungal susceptibility testing, susceptibility testing of anaerobes and interpretative reading and expert rules in susceptibility testing. Antifungal susceptibility testing (AFST) Breakpoints and methods for susceptibility testing of yeasts, moulds and dermatophytes are developed and validated by the EUCAST subcommittee on AFST. New and revised documents open for consultation will until accepted be published in the EUCAST News section together with all other consultations from EUCAST. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) EUCAST Definitive Document (E.Def) 9.3.2 includes guidelines for antifungal susceptibility testing on Aspergillus spp.